Welcome to the Medical Science Review

Medical Science Review (MSR) has developed as an independent title in 2014 as a continuation of highly successful Review Section of the Medical Science Monitor (since 1995). The aim of the Journal is to gather review articles across all medical disciplines, thereby integrating international medical knowledge. Medical Science Review has adopted the Open Access publishing model which enables free access... read more

Published: 2015-11-24

Diabetic Foot Ulcers: A Review of Evaluation, Prevention, and Treatment

Cyntia Saenz, Nishaal Antony, Mohamed Teleb, German Hernandez

(Southern New Mexico Family Medicine Residency, Las Cruces, NM, USA)

Med Sci Rev 2015; 2:156-160

DOI: 10.12659/MSRev.896162

ABSTRACT: Diabetes mellitus is a systemic chronic disease with multiple complications, such as microvascular and macrovascular diseases. Prevalence increases with age, with a growing number of patients affected each year. The microvascular complications include, but are not limited to, neuropathy, nephropathy, and retinopathy. Due to the increased incidence of small vessels disease in uncontrolled diabetes, many complications arise in the lower extremities, especially the foot. Lack of circulation and increased bony deformities induce multiple non-healing ulcers. Because diabetic patients are immunocompromised by default, they are prone to infection from multiple pathogenic organisms. There is a strong correlation between non-healing diabetic ulcers, amputation, and increased mortality rate if left untreated. Prevention is still a key element in decreasing the complications associated with these ulcers. This review will focus on diabetic foot ulcers, with an extensive evaluation of the literature on grading systems and associated treatment options.

Keywords: Amputation, Diabetes Mellitus, Diabetic Foot, osteomyelitis, Skin Ulcer

Published: 2015-11-23

Calorie Restriction and Epilepsy

Zheng Xiao, Liwei Tang

Med Sci Rev 2015; 2:150-155

DOI: 10.12659/MSRev.896553

Published: 2015-11-23

Is Retrograde Intrarenal Surgery Better Than Percutaneous Nephrolithotomy for Treatment of Renal Stones >...

Bin Xie, Chao Lu, Yongshi Qi, Changwen Zhang, Hao Ding, Yong Xu

Med Sci Rev 2015; 2:143-149

DOI: 10.12659/MSRev.895735