ISSN 2373-2490


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Medical Science Review (MSR) has developed as an independent title in 2014 as a continuation of highly successful Review Section of the Medical Science Monitor (since 1995). The aim of the Journal is to gather review articles across all medical disciplines, thereby integrating international medical knowledge. Medical Science Review has adopted the Open Access publishing model which enables free access... read more

Published: 2019-02-19

Progress in Radiofrequency for Trigeminal Neuralgia: Extracranial Non-Gasserian Ganglion Radiofrequency Thermocoagulation

Bing Huang, Yongxiang Luo, Yajing Chen, Ming Yao

(Department of Anesthesiology and Pain Medical Center, First Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China (mainland))

Med Sci Rev 2019; 6:1-6

DOI: 10.12659/MSRev.913518

ABSTRACT: Radiofrequency has been used for nearly half a century in the treatment of trigeminal neuralgia, and it has become one of the predominant treatments for trigeminal neuralgia. At present, radiofrequency has demonstrated substantial progress. However, the technique has limitations such as low branch selectivity, and individuals who undergo such treatments are at higher risk of intracranial hemorrhage and intracranial infection associated with intracranial puncture. In this review, we aimed to assess the efficacy of radiofrequency of the extracranial non-semilunar ganglion for trigeminal neuralgia. We changed the target of radiofrequency from the traditional intracranial semilunar ganglion to the cranial foramen (such as superior orbital foramen, foramen rotundum, and oval foramen) to improve branch selectivity and lower the risks of intracranial hemorrhage and intracranial infection associated with intracranial puncture. Moreover, we briefly assessed the technique in terms of therapeutic target, puncture approach, puncture imaging guidance, puncture needle, parameter setting, indications, and comfort during the procedure.

Keywords: Pulsed Radiofrequency Treatment, Trigeminal Ganglion, Trigeminal Neuralgia

Published: 2018-11-08

The Role of Food-Drug-Cytochrome P450 Interactions in Breast Cancer

Claudia Relats, Leila Sadeghi, Eveline Zbären, Helena Jenzer

Med Sci Rev 2018; 5:25-34

DOI: 10.12659/MSRev.911528

Published: 2018-09-04

Role of the Wnt/b-Catenin Pathway Inhibitor Sclerostin in Chronic Kidney Disease-Mineral and Bone Disorde...

Chao Zheng, Huang Ding, Linjun Qin, Ali Xiong, Jiulong Wang, Changqing Yin

Med Sci Rev 2018; 5:19-24

DOI: 10.12659/MSRev.911671